Cephalexin-related nephropathy
S. Verma and E. Kieff
Hematuria and eosinophilia developed in two patients being treated for
bacterial endocarditis with 20 or 24 gm/day of cephalexin given orally
together with probenecid (Benemid). One patient had a concurrent transient
increase in serum creatinine; both patients had a history of penicillin
allergy and had previously received cephalexin intravenously. All
abnormalities promptly remitted following discontinuation of therapy.
