Acute heat stroke. Epidemiologic, biochemical, renal, and coagulation studies
T. F. O'Donnell Jr
Fifteen Marine recruits with acute heat stroke were examined for (1)
predisposing factors, (2) blood coagulation disturbances, (3) renal
function abnormalities, and (4) blood composition alterations.
Epidemiologic data identified the following risk factors; previous
residence in a temperate climate, first phase of training, fatigue, and
strenuous exercise in hot, humid conditions. Results of blood coagulation
studies disclosed an increase in prothrombin and partial thromboplastin
times, with a decrease in platelet count, probably indicating a transient,
low-grade consumptive process. Blood urea nitrogen and creatinine levels
and creatinine clearance were normal. Only mild elevations of SGOT, SGPT,
and lactic dehydrogenase levels were noted, and in combination with
clinical observations, they argued against significant muscle damage. No
deaths or instances of renal failure occurred.
