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Technetium Tc 99m Macroaggregated Albumin Lung ScansUse in Chronic Childhood Asthma
John S. Hyde, MD;
Donald F. Koch, MD;
Paul D. Isenberg, MD;
Peter Werner, MD
JAMA. 1976;235(11):1125-1130.
Abstract
Serial roentgenograms and technetium Tc 99m macroaggregated albumin lung scans were done simultaneously in 30 bronchodilator-dependent asthmatic children and young adults during both relative remission and attacks of status asthmaticus.
When chest roentgenograms showed air trapping and increased peribronchial vascular markings associated with persistent perfusion defects, the children benefited from further laboratory studies and continuous comprehensive therapy.
Serial scans provided information about underperfusion that was not discernible either by roentgenograms or by usual blood gas studies. Also, lung scans are easier to obtain in children with long-standing asthma than are detailed pulmonary tests. In our study, technetium Tc 99m macroaggregated albumin scans showed persistent regional perfusion defects in 20 children with chronic asthma during relative remission and exacerbations.
(JAMA 235:1125-1130, 1976)
Author Affiliations
From the departments of pediatrics (Dr Hyde) and radiology (Dr Koch), the Rush Medical School, the Rush Medical Center (Dr Isenberg), and the Department of Medicine, the Abraham Lincoln School of Medicine (Dr Werner), Chicago. Dr Isenberg is a trainee in allergy and clinical immunology.
Footnotes
Read before the American Academy of Pediatrics, Oct 15, 1972, New York.
Reprint requests to Rush Medical Center, 1753 W Congress Pkwy, Chicago, IL 60612 (Dr Hyde).
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