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Charles L. Lewis, MB, ChB, FFR; Eileen Paterson, MD

JAMA. 1976;235(7):747-748.

Abstract
Significant peripheral white blood cell depression was noted in 75% of postmastectomy patients receiving chest wall and nodal irradiation and in 50% of patients receiving only peripheral nodal irradiation. Leukopenia was documented for as long as 36 months following therapy. With the current trend to earlier institution of chemotherapy, the routine use of postoperative irradiation must be reevaluated.

(JAMA 235:747-748, 1976)

Author Affiliations
From the Department of Radiation Oncology, Rochester General Hospital, Rochester, NY.

Footnotes
Reprint requests to Department of Radiation Oncology, 1425 Portland Ave, Rochester, NY 14621 (Dr Paterson).

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