This Article  • References  • Full text PDF  • Correction  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

A Report From the ACS/NIH Bone Marrow Transplant Registry

Prepared by the Advisory Committee of the Bone Marrow Transplant Registry

JAMA. 1976;236(10):1131-1135.

Abstract
Bone marrow transplantation from HLA-matched allogeneic donors was used to treat two series of patients with severe aplastic anemia. No significant differences were detected in all comparisons made between the Registry series (38 patients) and the Seattle series (24 patients), and pooled data from the two series were used in the analyses. Currently, 55% of the patients who received bone marrow transplants within three months of diagnosis are alive, but only 13% of the patients who received bone marrow transplants more than nine months after diagnosis are alive. The difference between the two groups was significant (P <.02). Patients less than 21 years of age had a significantly higher survival rate than those patients who were 21 years or older at the time of transplantation (P <.02). Survival rates were significantly higher for patients who had received 15 or fewer pretransplant transfusions than those who received more (P <.05).

(JAMA 236:1131-1135, 1976)

Author Affiliations
From the American College of Surgeons/National Institutes of Health, Organ Transplant Registry, Chicago.

Footnotes
Read in part at the Fourth Annual Conference of the International Society for Experimental Hematology, Split, Yugoslavia, Sept 21-24, 1975, and at the First International Symposium on the Immunobiology of Bone Marrow Transplantation, New York, Nov 10-13, 1975.

Reprint requests to Mount Sinai Medical Center, 950 N 12th St, Milwaukee, Wi 53233 (Dr Bortin).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Hematopoietic Cell Transplantation for Benign Hematological Disorders and Solid Tumors
Storb et al.
ASH Education Book 2003;2003:372-397.
ABSTRACT | FULL TEXT  

Decreased Rejection and Improved Survival of First and Second Marrow Transplants for Severe Aplastic Anemia (A 26-Year Retrospective Analysis)
Stucki et al.
Blood 1998;92:2742-2749.
ABSTRACT | FULL TEXT  

Allogeneic Bone Marrow Transplantation for 144 Patients With Severe Aplastic Anemia
Bortin et al.
JAMA 1981;245:1132-1139.
ABSTRACT  

Marrow Transplantation in Thirty "Untransfused" Patients with Severe Aplastic Anemia
STORB et al.
ANN INTERN MED 1980;92:30-36.
ABSTRACT  

Bone Marrow Transplantation for Acute Myeloblastic Leukemia
Bortin and Rimm
JAMA 1978;240:1245-1252.
ABSTRACT