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Death Due to Agranulocytosis and Pneumonia

Elizabeth Uhlmann Neel, MD

JAMA. 1976;236(13):1493-1494.

Abstract
Infectious mononucleosis (IM) is usually considered a benign disease. Agranulocytosis developed in a young college student 14 days after the onset of IM. Fulminant staphylococcal pneumonia and bilateral pulmonary infarcts resulted, and the patient died 4 1/2 hours after admission to a hospital.

Agranulocytosis secondary to IM may be more prevalent than previously thought. A review of the literature indicated that infection developed in 57.9% of the patients with IM and extreme neutropenia and 45.4% of the infected patients died.

(JAMA 236:1493-1494, 1976)

Author Affiliations
From the Department of Student Health, California State University, San Jose, Calif.

Footnotes
Reprint requests to 1555 Clay Dr, Los Altos, CA 94022 (Dr Neel).

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