Primary and secondary hypothyroidism in nasopharyngeal carcinoma
M. B. Rosenthal and I. D. Goldfine
We investigated the thyroid and pituitary functions of six of the seven
patients with nasopharyngeal carcinoma who had been previously treated with
external radiation, and who were seen at the San Francisco Veterans
Administration Hospital within a recent 18 month period. Two patients had
primary hypothyroidism, and four had secondary hypothyroidism. These
findings suggest that thyroid and pituitary abnormalities are frequent
complications of both nasopharyngeal carcinoma and its treatment.