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Treatment With Adjuvant Immunotherapy

Courtney M. Townsend, Jr, MD; Frederick R. Eilber, MD; Donald L. Morton, MD

JAMA. 1976;236(19):2187-2189.

Abstract
Because there is evidence for an active immunologic response against sarcoma, a clinical trial of adjuvant immunotherapy using bacillus Calmette-Guérin (BCG) and tumor cell vaccine was begun.

Eleven of 18 patients with localized soft tissue sarcoma who received immunotherapy are free of disease, compared to only 5 of 15 treated by operation alone who are free of disease. Furthermore, immunotherapy also prolonged the median disease-free interval from 7.3 months to 15 months in the patients who experienced recurrence of their disease.

(JAMA 236:2187-2189, 1976)

Author Affiliations
From the Division of Oncology and the Department of Surgery (Drs Townsend, Eilber, and Morton), UCLA Medical School, Los Angeles; and the Surgical Services, Sepulveda Veterans Administration Hospital, Sepulveda, Calif (Drs Townsend, Eilber, and Morton).

Footnotes
Reprint requests to the Division of Oncology, UCLA School of Medicine, The Center for the Health Sciences, Los Angeles, CA 90024 (Dr Morton).

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