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Long-Term Results

Loren T. DeWind, MD; J. Howard Payne, MD

JAMA. 1976;236(20):2298-2301.

Abstract
Since 1962, jejunoileal bypass has been performed on 59 male and 171 female subjects, aged 18 to 55 years; these patients were followed clinically. Postoperative weight loss at two years averaged 37% in men and 35% in women. Hypokalemia (23%), hypocalcemia (22%), hypoalbuminemia (9%), metabolic acidosis (14%), elevated liver enzyme values (41%), and hyperbilirubinemia (6%), were the most commonly encountered blood chemical alterations. Complications were arthritis syndrome (men, 8%; women, 19%), urinary calculi (men, 24%; women, 10%), cholelithiasis (men, 10%; women, 9%), liver impairment (men, 2%; women, 6%), and major emotional upset (men, 8%; women, 9%). Forty-nine percent of the men and 51% of the women required rehospitalization for management of complications, surgery for hernia, anorectal disorders, nutritional support, and metabolic study. There were 19 bypass-related deaths (8%), including 10 due to liver failure.

(JAMA 236:2298-2301, 1976)

Author Affiliations
From the Departments of Medicine (Dr DeWind) and Surgery (Dr Payne), University of Southern California School of Medicine, and the Hospital of the Good Samaritan Medical Center (Drs DeWind and Payne), Los Angeles.

Footnotes
Reprint requests to 9818 Paramount Blvd, Downey, CA 90240 (Dr DeWind).

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