You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT JAMA
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 236 No. 6, August 9, 1976 TABLE OF CONTENTS
  JAMA
  •  Online Features
  ARTICLE
 This Article
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citing articles on HighWire
 •Contact me when this article is cited
 Related Content
 •Similar articles in JAMA

Mixed venous oxygen tension and hyperlactatemia. Survival in severe cardiopulmonary disease

P. Kasnitz, G. L. Druger, F. Yorra and D. H. Simmons

Mixed venous oxygen tension (PVo2), cardiac output (Q), and arterial oxygen tension (Pao2) were measured in 20 patients with severe cardiac or pulmonary disease or both to determine which of these variables would best predict hyperlactatemia and survival. There was no correlation between Pao2 and either hyperlactatemia or survival, possibly because all oxygen tensions were greater than 40 mm Hg. There was a good correlation between Q and both hyperlactatemia and survival, and a slightly better correlation between PVo2 and both hyperlactatemia and survival. Mixed venous oxygen tension, a reflection of both Pao2 and Q, was a better predictor of hyperlactatemia and death than either arterial Pao2 or Q alone. It is also more easily measured and, therefore, more clinically useful than either Q, as a predictor of anaerobiosis and survival, or blood lactate concentration, as a predictor of survival. A mixed venous oxygen tension below 28 mm Hg was usually associated with hyperlactatemia and was always associated with death.

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Clinical utility of B-type natriuretic peptide in early severe sepsis and septic shock.
Rivers et al.
J Intensive Care Med 2007;22:363-373.
ABSTRACT  

Optimal hemoglobin concentration and high altitude: a theoretical approach for Andean men at rest
Villafuerte et al.
J. Appl. Physiol. 2004;96:1581-1588.
ABSTRACT | FULL TEXT  

CHRONIC NONPULSATILE BLOOD FLOW. III. EFFECTS OF PUMP FLOW RATE ON OXYGEN TRANSPORT AND UTILIZATION IN CHRONIC NONPULSATILE BIVENTRICULAR BYPASS
Tominaga et al.
J. Thorac. Cardiovasc. Surg. 1996;111:863-872.
ABSTRACT | FULL TEXT  

Analytic Reviews : Hemodynamic Management of the Adult Respiratory Distress Syndrome
Courtney Broaddus et al.
J Intensive Care Med 1987;2:190-213.
ABSTRACT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1976 American Medical Association. All Rights Reserved.