Edema associated with ibuprofen therapy
R. T. Schooley, P. F. Wagley and P. S. Lietman
A 15-kg weight gain developed in a patient during the third week of
ibuprofen therapy. The edema disappeared with discontinuation of the drug
regimen and did not reappear during a subsequent six-month observation
period. It should be recognized that ibuprofen may be associated with salt
and water retention in the same fashion as previously described with
phenylbutazone and indomethacin.