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  Vol. 237 No. 16, April 18, 1977 TABLE OF CONTENTS
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Edema associated with ibuprofen therapy

R. T. Schooley, P. F. Wagley and P. S. Lietman

A 15-kg weight gain developed in a patient during the third week of ibuprofen therapy. The edema disappeared with discontinuation of the drug regimen and did not reappear during a subsequent six-month observation period. It should be recognized that ibuprofen may be associated with salt and water retention in the same fashion as previously described with phenylbutazone and indomethacin.

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