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Vol. 237 No. 17, April 25, 1977 TABLE OF CONTENTS
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Circulating autoantibody against human myoglobin in polymyositis

M. Nishikai and M. Homma

A passive hemagglutination method for circulating autoantibody to purified human skeletal muscle myoglobin has been developed. This antibody was detected in the sera of 22 of 31 patients with polymyositis. The incidence and the antibody titers were significantly higher than in other myopathies such as myasthenia gravis (P less than .02), Duchenne-type muscular dystrophy (P less than .001), and other conditions (P less than .001). This new antibody test is useful in diagnosing polymyositis.




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