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Clyde Thornsberry, PhD; Harold Jaffee, MD; Stuart T. Brown, MD; Teresa Edwards, RN; James W. Biddle, MS; Sumner E. Thompson, MD, MPH

JAMA. 1977;237(22):2405-2406.

Abstract
Neisseria gonorrhoeae resistant to high levels of spectinomycin (more than 2,048 µg/ml), were isolated from specimens obtained from a patient with urethritis. The bacterial resistance to spectinomycin is probably due to ribosomal changes that are a result of a chromosomal mutation. If spectinomycin fails to cure gonorrhea, spectinomycin resistance should be considered.

(JAMA 237:2405-2406, 1977)

Author Affiliations
From the Bacteriology Division (Dr Thornsberry and Mr Biddle), Bureau of Laboratories and the Venereal Disease Control Division (Drs Jaffee, Brown, and Thompson), and the Bureau of State Services, Center for Disease Control, Public Health Service, US Department of Health, Education, and Welfare, and the Fulton County Health Department (Dr Brown and Ms Edwards), Atlanta.

Footnotes
Reprint requests to Bacteriology Division, Bureau of Laboratories, Center for Disease Control, Atlanta, GA 30333 (Dr Thornsberry).

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