Pregnancy outcome in women with sickle cell trait
P. Blattner, H. Dar and H. M. Nitowsky
A prospective study was carried out to discern the outcome of pregnancy and
distribution of birth weights of infants delivered of 85 women with sickle
cell trait (AS) compared with a control group of 85 women with normal
hemoglobin (AA) who were matched for race, age, parity, and sex of
offspring. The distribution of birth weight of offspring of primiparous and
multiparous women and the proportion of low-birth-weight infants did not
differ significantly between infants born to mothers with AS and those in
the control group. Similarly, there was no statistically significant
difference between the birth weight of infants born to primipara or
multipara. Also, the overall incidence of complications among women with AS
did not differ from the incidence in the control group. The findings do not
support previous reports that there may be definable pathologic correlates
of childbearing in women with AS.
