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R. H. Ruvalcaba, S. A. Myhre, E. C. Roosen-Runge and J. B. Beckwith
Members of two kindreds had mental deficiency and megalotestes. The
familial occurrence suggests an X-linked recessive trait or
autosomal-dominant trait with male sex limitation. The increased testicular
size was apparently due to excess fluid content.
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Macroorchidism in FMR1 Knockout Mice Is Caused by Increased Sertoli Cell Proliferation during Testicular Development
Slegtenhorst-Eegdeman et al. Endocrinology 1998;139:156-162. ABSTRACT
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