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  Vol. 238 No. 24, December 12, 1977 TABLE OF CONTENTS
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Hepatitis B Surface Antigen (HBsAg) and Antibody to HBsAg

Prevalence in Homosexual and Heterosexual Men

Dale E. Dietzman, MD; James P. Harnisch, MD; C. George Ray, MD; E. Russell Alexander, MD; King K. Holmes, MD, PhD

JAMA. 1977;238(24):2625-2626.


Abstract

The prevalence rates of serum hepatitis B surface antigen (HBsAg) and antibody to HBsAg (anti-HBs) were 5.6% and 34% in 144 homosexual men in Seattle. Prevalence rates were only 0.9% and 3.6% in 111 heterosexual male venereal disease clinic patients with nongonococcal urethritis, and also 0.9% and 3.6% in 111 healthy men undergoing routine physical examinations. Thus, previous exposure to hepatitis B virus (HBV) was estimated to be 8.8 times greater for homosexual men than for heterosexual men. Four of four HBsAg positive sera from homosexual men were subtyped as "ad," whereas subtype "ay" is preponderant in intravenous drug abusers. Future public health measures to control HBV infection should address the prevention of sexually transmitted HBV infection among homosexual men.

(JAMA 238:2625-2626, 1977)



Author Affiliations

From the Departments of Pediatrics (Drs Dietzman and Ray), Laboratory Medicine (Drs Dietzman and Ray), Microbiology (Drs Dietzman and Ray), Epidemiology (Dr Alexander), International Health (Dr Alexander) and Medicine (Drs Harnisch and Holmes), University of Washington, Seattle; the Children's Orthopedic Hospital and Medical Center, Seattle; and the United States Public Health Service Hospital, Seattle.


Footnotes

Reprint requests to the Division of Infectious Diseases, United States Public Health Service Hospital, 1131 14th Ave S, Seattle, WA 93114 (Dr Holmes).



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