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Occurrence in Adult Contacts of Pediatric Patients With Gastroenteritis

Hyun W. Kim, MD; Carl D. Brandt, PhD; Albert Z. Kapikian, MD; Richard G. Wyatt, MD; Julita O. Arrobio, MD; William J. Rodriguez, MD; Robert M. Chanock, MD; Robert H. Parrott, MD

JAMA. 1977;238(5):404-407.

Abstract
Sixty-four adult family contacts of 61 young patients with gastroenteritis were included in a study for evidence of concurrent infection with the human reovirus-like agent (HRVLA) of infantile diarrhea. Evidence of infection was detected in 26 (41%) of the adult contacts. The HRVLA infection occurred significantly more often among adult contacts of pediatric patients infected with HRVLA (55%) than among contacts of young patients not infected with the agent (17%). Mild cases of gastroenteritis developed in only three of the contacts infected with HRVLA.

(JAMA 238:404-407, 1977)

Author Affiliations
From the Virology Section, Research Foundation of Children's Hospital National Medical Center, George Washington University Medical Center, Washington, DC, and the Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.

Footnotes
Reprint requests to Virology Section, Research Foundation of Children's Hospital National Medical Center, 111 Michigan Ave, Washington, DC 20010 (Dr Kim).

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