Childhood trachoma in a nonendemic area. Danish trachoma patients and their close contacts, 1963 to 1973
C. H. Mordhorst, S. P. Wang and J. T. Grayston
During ten years of study of Chlamydia trachomatis eye infections, trachoma
was diagnosed in 14 Danish patients with onset during childhood. Clinical
findings in the eye were characteristic of classical trachoma. The
infecting C trachomatis immunotype was identified in all but one case. At
the time of diagnosis, seven patients were still children (6 to 10 years of
age), three were teenagers, and four were adults. In five young girls the
disease was extremely severe. Delay in proper diagnosis and adequate
therapy contributed to the prolongation and severity of the disease.
Failure to diagnose is attributed to widespread opinion and teaching of
physicians in Western countries that trachoma eye disease has disappeared.
Studies of family members and other contacts of the patients contributed to
an understanding of the pathogenesis of this disease. The source of initial
eye infection with C trachomatis organisms in these cases was thought to be
the birth canal. It was further postulated that reinfection of the eyes of
these children occurred either from a reservoir in their own or their
mother's genital tract.
