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Thrombophlebitis in Systemic Lupus Erythematosus
Brian Peck, MD;
Gary S. Hoffman, MD;
Walter A. Franck, MD
JAMA. 1978;240(16):1728-1730.
Abstract
Thrombophlebitis occurred in 14 (12.2%) of 114 patients with active systemic lupus erythematosus (SLE). Abnormal clotting occurred despite the presence of thrombocytopenia or circulating anticoagulants in some of the patients, and the development of pulmonary emboli was verified in seven. Although infrequently reported, the association of thrombophlebitis with active SLE is apparently not uncommon. While there were no features that distinguished this group of patients from other groups of patients with SLE, there are some possible mechanisms. Recognition of this complication of SLE is important because of the frequent occurrence of SLE-induced pleuritis and its similarity to the pain of pulmonary emboli.
(JAMA 240:1728-1730, 1978)
Author Affiliations
From the Department of Medicine, Connective Tissue Diseases Section, Dartmouth-Hitchcock Medical Center, Hanover, NH (Drs Peck, Hoffman), Department of Medicine, White River Junction Veterans Administration Hospital, White River Junction, Vt (Drs Peck and Hoffman), and the Mary Imogene Bassett Hospital, Cooperstown, NY (Drs Hoffman and Franck).
Footnotes
Reprint requests to Department of Medicine, Rheumatology Section, Mary Imogene Bassett Hospital, Cooperstown, NY 13326 (Dr Hoffman).
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