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  Vol. 240 No. 18, October 27, 1978 TABLE OF CONTENTS
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Minoxidil Treatment of Malignant Hypertension

Recovery of Renal Function

Friedrich C. Luft, MD; Richard Bloch, MD; James J. Szwed, MD; Carlene M. Grim, RN, MS; Clarence E. Grim, MD

JAMA. 1978;240(18):1985-1987.


Abstract

We treated eight severely hypertensive, long-term hemodialysis patients who failed to respond to ultrafiltration or conventional medication with minoxidil rather than with bilateral nephrectomy. Control of blood pressure and relief of symptoms was achieved in all eight. In addition, three of the patients, who were all severely oliguric, recovered sufficient renal function to allow the discontinuation of dialysis. Two are presently doing well, while one died of causes unrelated to uremia or minoxidil therapy. We presently reserve bilateral nephrectomy for those hypertensive dialysis patients who are awaiting transplantation.

(JAMA 240:1985-1987, 1978)



Author Affiliations

From the Renal Section and the Specialized Center for Research-Hypertension, Department of Medicine, Indiana University School of Medicine, Indianapolis.


Footnotes

Reprint requests to Fesler Hall 110, Indiana University Medical Center, 1100 W Michigan St, Indianapolis, IN 46202 (Dr Luft).



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