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Megavitamins for Minimal Brain DysfunctionA Placebo-Controlled Study
L. Eugene Arnold, MEd, MD;
James Christopher, MD;
Robert D. Huestis, MD;
Donald J. Smeltzer, MA
JAMA. 1978;240(24):2642-2643.
Abstract
Preliminary to a stimulant comparison study, 31 children with minimal brain dysfunction randomly received either placebo or a megavitamin combination. During a two-week trial, only two children responded so well that stimulants were not considered necessary; both were in the placebo group. Change scores from pretest to posttest on four blind ratings by teachers and parents did not show a significant difference between the placebo and vitamin groups.
(JAMA 240:2642-2643, 1978)
Author Affiliations
From the Departments of Psychiatry (Drs Arnold and Smeltzer) and Pediatrics (Dr Arnold), Ohio State University, Columbus; the Department of Psychiatry (Dr Christopher), Richland Neuropsychiatric Hospital, Mansfield, Ohio; and the Holzer Medical Center Clinic (Dr Huestis), Gallipolis, Ohio.
Footnotes
Reprint requests to Department of Psychiatry, Ohio State University College of Medicine, 473 W 12th Ave, Columbus, OH 43210 (Dr Arnold).
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