Ankylosing spondylitis and hyperparathyroidism
R. Goldin, A. S. Brickman, S. G. Massry and R. Bluestone
An attempt was made to determine whether a relationship exists between
ankylosing spondylitis (AS) and hyperparathyroidism (HP). Twenty patients
with definite AS, studied for biochemical evidence of HP, did not show
consistent abnormalities in serum calcium, phosphorus, alkalinephosphatase,
or parathyroid hormone levels or in bone-density measurements. Reviewing
roentgenograms of 39 patients with HP showed one patient with sacroiliitis,
and one of the 28 hyperparathyroid patients tissue-typed as HLA
B27-positive. Both AS and HP are independent entities that have no
causative or pathological relationship to each other.