Adverse reactions to cromolyn
G. A. Settipane, D. E. Klein, G. K. Boyd, J. H. Sturam, H. B. Freye and J. K. Weltman
The frequency of adverse reactions (dermatitis, myositis, and
gastroenteritis) to cromolyn sodium in asthmatic patients was 2% (B/375).
Reactions were non-life-threatening and completely reversible. Immunologic
evaluations, including skin and serum tests for immediate and delayed
reactivity, all were negative. Adverse reactions to cromolyn do not appear
to be based on an immunologic mechanism. Cromolyn appears to be a safe drug
for the treatment of asthma.