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Adverse Reactions to Cromolyn
Guy A. Settipane, MD;
Donald E. Klein, MD;
George K. Boyd, MD;
Jorge H. Sturam, MD;
Henry B. Freye, MD;
Joel K. Weltman, MD, PhD
JAMA. 1979;241(8):811-813.
Abstract
The frequency of adverse reactions (dermatitis, myositis, and gastroenteritis) to cromolyn sodium in asthmatic patients was 2% (8/375). Reactions were non-life-threatening and completely reversible. Immunologic evaluations, including skin and serum tests for immediate and delayed reactivity, all were negative. Adverse reactions to cromolyn do not appear to be based on an immunologic mechanism. Cromolyn appears to be a safe drug for the treatment of asthma.
(JAMA 241:811-813, 1979)
Author Affiliations
From the Division of Allergy, Department of Medicine and Pediatrics, Rhode Island Hospital, and the Program in Medicine, Brown University, Providence, RI.
Footnotes
Reprint requests to Division of Allergy, Rhode Island Hospital, Providence, RI 02902 (Dr Settipane).
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