This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Association With Low Radioactive Iodine Uptake

Robert H. Eckel, MD; William L. Green, MD

JAMA. 1980;243(14):1454-1456.

Abstract
A patient with previously diagnosed Graves' hyperthyroidism had a transient episode of thyrotoxicosis three months postpartum. This was associated with a diffusely enlarged thyroid gland, a rise in antithyroid microsomal antibody titer, a 24-hour radioactive iodine uptake (RAIU) of 1%, and an aspiration biopsy specimen suggestive of chronic lymphocytic thyroiditis. An alternative cause for the depressed RAIU was not discovered. This case would suggest that patients with previously diagnosed Graves' disease can have thyrotoxicosis without an enhanced RAIU and that the postpartum thyrotoxic syndrome may involve an immunologic injury causing a release of preformed thyroid hormone.

(JAMA 243:1454-1456, 1980)

Author Affiliations
From the Department of Medicine, University of Washington School of Medicine, Seattle.

Footnotes
Reprint requests to Harborview Medical Center, 325 Ninth Ave, Seattle, WA 98104 (Dr Green).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Postpartum Thyroiditis and Autoimmune Thyroiditis in Women of Childbearing Age: Recent Insights and Consequences for Antenatal and Postnatal Care
Muller et al.
Endocr. Rev. 2001;22:605-630.
ABSTRACT | FULL TEXT  

Postpartum Thyroiditis in Women with Hypothyroidism Antedating Pregnancy?
Caixàs et al.
J. Clin. Endocrinol. Metab. 1999;84:4000-4005.
ABSTRACT | FULL TEXT  

Postpartum Lymphocytic Thyroiditis: Prevalence, Clinical Course, and Long-term Follow-up
Nikolai et al.
Arch Intern Med 1987;147:221-224.
ABSTRACT  

Postpartum Thyroid Dysfunction
Goldman
Arch Intern Med 1986;146:1296-1299.
ABSTRACT  

Silent (Painless) Thyroiditis: Evidence of a Geographic Variation in Frequency
Vitug and Goldman
Arch Intern Med 1985;145:473-475.
ABSTRACT  

Familial Postpartum Transient Hyperthyroidism
Singer and Gorsky
Arch Intern Med 1985;145:240-242.
ABSTRACT  

Recurrence and Heterogeneity in Painless Thyrotoxic Lymphocytic Thyroiditis: Report of Five Cases
Taylor and Sheeler
JAMA 1982;248:1085-1088.
ABSTRACT