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Morven S. Edwards, MD; Claudia V. Jackson, RN; Carol J. Baker, MD

JAMA. 1981;245(20):2044-2046.

Abstract
Infants who are the products of multiple births comprise a newly defined group of patients at increased risk for the development of invasive, group B streptococcal infection. This report summarizes the clinical and bacteriologic features of 11 sets of twins and one set of triplets in which one (nine sets) or more (three sets) infants had proved early- or late-onset group B streptococcal infection. Reasons for the enhanced susceptibility of index patients and their siblings are discussed. On the basis of these observations, an empirical approach is proposed for the treatment of the apparently noninvolved sibling of a twin with invasive group B streptococcal infection.

(JAMA 1981;245:2044-2046)

Author Affiliations
From the Departments of Pediatrics, Microbiology, and Immunology, Baylor College of Medicine, Houston.

Footnotes
Reprint requests to Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030 (Dr Edwards).

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