This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (14)  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

A Form of Polyneuritis?

Kedar K. Adour, MD; Monroe A. Sprague, MD; Raymond L. Hilsinger, Jr, MD

JAMA. 1981;246(14):1564-1567.

Abstract
Vestibular vertigo traditionally has been considered to be of viral origin and some forms (acute vestibular neuronitis, acute labyrinthitis, acute vertigo) may be manifestations of a viral cranial polyneuritis. To test this hypothesis, otoneurologic signs and serum complement-fixation titers to herpes simplex and herpes zoster were determined in 16 patients with acute vertigo during their attack and several weeks later. One hundred unselected patients seen for nonotoneurologic problems served as control subjects. In addition to vestibular nerve abnormality, all patients with vertigo had some form of cranial nerve abnormality that cleared within four weeks of onset. These transient acute cranial nerve findings in patients with vestibular vertigo support the concept of inflammatory polyneuritis, and preliminary studies indicate that an anti-inflammatory agent such as prednisone may be the preferred treatment.

(JAMA 1981;246:1564-1567)

Author Affiliations
From the Cranial Nerve Research Clinic, Department of Otolaryngology, Kaiser-Permanente Medical Center, Oakland, Calif.

Footnotes
Reprint requests to Department of Otolaryngology, Kaiser-Permanente Medical Center, 280 W MacArthur Blvd, Oakland, CA 94611 (Dr Adour).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

The Beneficial Effect of Methylprednisolone in Acute Vestibular Vertigo
Ariyasu et al.
Arch Otolaryngol Head Neck Surg 1990;116:700-703.
ABSTRACT