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Muscle Involvement in Systemic Lupus Erythematosus
George C. Tsokos, MD;
Haralampos M. Moutsopoulos, MD;
Alfred D. Steinberg, MD
JAMA. 1981;246(7):766-768.
Abstract
Of 228 patients with systemic lupus erythematosus (SLE) admitted to our inpatient service during a 6.5-year period, 18 (8%) had prominent muscle disease. In the majority of these patients, myositis occurred at the time of diagnosis of SLE. The creatine phosphokinase level was normal in all but one of these patients; however, the serum aldolase level was frequently elevated. All patients responded promptly to corticosteroid treatment.
(JAMA 1981;246:766-768)
Author Affiliations
From the Arthritis and Rheumatism Branch, National Institute of Arthritis, Metabolism, and Digestive Diseases, National Institutes of Health, Bethesda, Md. Dr Moutsopoulos is now with the University of loannina, loannina, Greece.
Footnotes
Reprint requests to Arthritis and Rheumatism Branch, National Institute of Arthritis, Metabolism, and Digestive Diseases, National Institutes of Health, Bldg 10, Room 8D-19, Bethesda, MD 20205 (Dr Steinberg).
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