This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Lt Col Robert L. Jacobs, MC; Ralph S. Lowe, MD; Bobby Q. Lanier, MD

JAMA. 1982;247(1):40-42.

Abstract
A retrospective review of 740 charts of patients with a history of adverse reaction to tetanus toxoid immunization was undertaken. The most common reactions, by history, were local edema and tenderness (33%), fever (15%), and anaphylactoid response (33%). Three patients who had a vesicular eruption at the immunization site were found to have delayed hypersensitivity to mercury. Thirty percent of the patients had received tetanus toxoid within one year and 55% within five years of evaluation. Reactive responses to immediate skin tests were exceedingly rare (<1%). None of the challenge patients suffered an adverse reaction.

(JAMA 1982;247:40-42)

Author Affiliations
USAF

From the Allergy-Immunology Service, Wilford Hall USAF Medical Center, Lackland AFB, Tex.

Footnotes
The opinions and assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Air Force or the Department of Defense.

Reprint requests to Allergy-Immunology Service, Department of Medicine, Wilford Hall USAF Medical Center, Lackland AFB, TX 78236 (Dr Jacobs).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Phase I Trial of a CD8+ T-Cell Peptide Epitope-Based Vaccine for Infectious Mononucleosis
Elliott et al.
J. Virol. 2008;82:1448-1457.
ABSTRACT | FULL TEXT  

Transcutaneous Immunization Using Colonization Factor and Heat-Labile Enterotoxin Induces Correlates of Protective Immunity for Enterotoxigenic Escherichia coli
Yu et al.
Infect. Immun. 2002;70:1056-1068.
ABSTRACT | FULL TEXT  

Combination Vaccines for Childhood Immunization: Recommendations of the Advisory Committee on Immunization Practices (ACIP), the American Academy of Pediatrics (AAP), and the American Academy of Family Physicians (AAFP)
Committee on Infectious Diseases, 1998MIHNEAndash1 et al.
Pediatrics 1999;103:1064-1077.
FULL TEXT  

Allergic Reactions to Drugs and Biologic Agents
deShazo and Kemp
JAMA 1997;278:1895-1906.
ABSTRACT  

The Prevention of Tetanus in the Elderly
Richardson and Knight
Arch Intern Med 1991;151:1712-1717.
ABSTRACT  

Recommendations of the Immunization Practices Advisory Committee (ACIP) General Recommendations on Immunization
Arch Pediatr Adolesc Med 1989;143:1013-1019.
ABSTRACT  

General Recommendations on Immunization
JAMA 1989;262:339-340.
 

General Recommendations on Immunization: Guidelines from the Immunization Practices Advisory Committee
ANN INTERN MED 1989;111:133-142.
ABSTRACT  

Diphtheria, Tetanus, and Pertussis: Guidelines for Vaccine Prophylaxis and Other Preventive Measures: Recommendation of the Immunization Practices Advisory Committee
CENTERS FOR DISEASE CONTROL, DEPARTMENT OF HEALTH
ANN INTERN MED 1985;103:896-905.
ABSTRACT  

Leads from the MMWR
JAMA 1985;254:1009-1016.
 

Neurologic Complications of Tetanus Toxoid
Fenichel
Arch Neurol 1983;40:390-390.
ABSTRACT