Risks to children from computed tomographic scan premedication
A. A. Mitchell, C. Louik, P. Lacouture, D. Slone, P. Goldman and S. Shapiro
We observed serious adverse reactions after premedication for computed
tomographic (CT) head scans and therefore determined rates and risk factors
for such reactions among 106 hospitalized children monitored by an
intensive drug surveillance program. Reactions occurred in 13 patients
(13%), including four cases of life-threatening cardiorespiratory
depression or arrest after narcotic premedication. Other reactions included
CNS depression, behavior changes, voiding problems, and vomiting. The risk
of reaction was elevated in subjects who received high doses of a
premedication drug (relative risk, 5.2) and in those who received four or
more premedication (relative risk, 3.7). All life-threatening reactions
occurred among infants younger than 3 months, and two of these followed
medication with only morphine sulfate, in the recommended dose. Risks of
adverse reactions from premedication should be considered by physicians who
order CT scans for hospitalized children.
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ABSTRACT
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ABSTRACT
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ABSTRACT
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Results of a Pediatric Sedation Program on Head MRI Scan Success Rates and Procedure Duration Times
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ABSTRACT
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ABSTRACT
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ABSTRACT
