This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (37)  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

W. Lawrence Drew, MD, PhD; Richard C. Miner

JAMA. 1982;247(17):2389-2391.

Abstract
Clinically evident cytomegalovirus (CMV) infections developed in five patients after noncardiac surgery. Each of them had received several blood transfusions and had evidence of primary CMV infection. These five cases were identified in a single eight-month period, suggesting that this syndrome must be occurring with greater frequency than is commonly appreciated. Three of the five patients had undergone splenectomy, and review of the literature for documented cases of posttransfusion CMV mononucleosis following non-cardiac-bypass surgery disclosed an additional nine patients, five of whom had had splenectomies. This striking association suggests the possibility that the spleen plays a role in controlling the incidence or clinical manifestations of posttransfusion CMV infections. Alternatively, this association may only reflect the frequent requirement for many blood transfusions in this type of surgery.

(JAMA 1982;247:2389-2391)

Author Affiliations
From the Biskind Pathology Research Laboratory, Harold Brunn Institute for Medical Research, and the Departments of Medicine and Pathology and Laboratory Medicine, Mt Zion Hospital and Medical Center, San Francisco.

Footnotes
Reprint requests to Mt Zion Hospital and Medical Center, 1600 Divisadero St, San Francisco, CA 94115 (Dr Drew).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Reducing the Risk for Transfusion-transmitted Cytomegalovirus Infection
Sayers et al.
ANN INTERN MED 1992;116:55-62.
ABSTRACT