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Laurence S. Chaise, MD; Anthony J. Comerota, MD; Renate L Soulen, MD; Ronald N. Rubin, MD

JAMA. 1982;247(17):2397-2400.

Abstract
We report successful lysis of acute arterial calf thrombosis by intra-arterial streptokinase infusion seven hours after retroperitoneal dissection and repair of an ipsilateral common femoral artery laceration. No systemic effects or complications developed. Local intra-arterial thrombolytic therapy is more effective and safer than intravenous systemic therapy and may now be considered in the immediate postoperative period, providing the drug is delivered downstream from the operative site.

(JAMA 1982;247:2397-2400)

Author Affiliations
From the Departments of Diagnostic Radiology (Drs Chaise and Soulen), Surgery (Dr Comerota), and Internal Medicine (Dr Rubin), Temple University Health Sciences Center, Philadelphia.

Footnotes
Reprint requests to Department of Diagnostic Radiology, Temple University Hospital, 3401 N Broad St, Philadelphia, PA 19140 (Dr Soulen).

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