Selective intra-arterial streptokinase therapy in the immediate postoperative period
L. S. Chaise, A. J. Comerota, R. L. Soulen and R. N. Rubin
We report successful lysis of acute arterial calf thrombosis by
intra-arterial streptokinase infusion seven hours after retroperitoneal
dissection and repair of an ipsilateral common femoral artery laceration.
No systemic effects or complications developed. Local intra-arterial
thrombolytic therapy is more effective and safer than intravenous systemic
therapy and may now be considered in the immediate postoperative period,
providing the drug is delivered downstream from the operative site.