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In Vivo Comparison of Levothyroxine Preparations
LTC Angelita Ramos-Gabatin, MC;
MAJ James M. Jacobson, MC;
COL Robert L. Young, MC
JAMA. 1982;247(2):203-205.
Abstract
Two brands of levothyroxine sodium (Levothroid and Synthroid) were found not to be bioequivalents. Until a more precise standardization for levothyroxine sodium preparation is available, patients should be consistently treated with one brand name preparation. Adjustment of the dosage may be necessary if the treatment is switched from one brand name preparation to another.
(JAMA 1982;247:203-205)
Author Affiliations
USAF; USAF; USAF
From the Departments of Medicine, the USAF Medical Center Keesler, Keesler AFB, Biloxi, Miss (Dr Ramos-Gabatin), and the Wright-Patterson USAF Medical Center, Wright-Patterson AFB, Ohio (Dr Jacobson), and the Department of Endocrinology, Wilford Hall USAF Medical Center, Lackland AFB, San Antonio, Tex (Dr Young). Dr Young now resides in El Paso, Tex.
Footnotes
Reprint requests to Department of Medicine/ SGHM, USAF Medical Center Keesler, Keesler AFB, Biloxi, MS 39534 (Dr Ramos-Gabatin).
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