This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (54)  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

David S. Siscovick, MD, MPH; Noel S. Weiss, MD, DPH; Alfred P. Hallstrom, PhD; Thomas S. Inui, MD, ScM; Donald R. Peterson, MD, MPH

JAMA. 1982;248(23):3113-3117.

Abstract
To explore the relationship between vigorous physical activity and primary cardiac arrest (PCA), we identified, through emergency service incident reports, 163 cases of PCA aged 25 to 75 years. Control subjects matched for age, sex, residence, and the absence of prior clinical heart disease or major comorbidity were identified from the community. Spouses of subjects were interviewed to quantify leisure-time activity (LTA) during the prior year. Energy expended in high-intensity LTA, requiring 60% of maximum oxygen intake, was determined. The risk of PCA was 55% to 65% lower in persons in the two upper quartiles of high-intensity LTA than in persons without high-intensity LTA (95% confidence interval of relative risk, 0.22 to 0.85). Because this association was demonstrated in a clinically healthy population without prior morbidity, our data support the hypothesis that high-intensity LTA protects against PCA.

(JAMA 1982;248:3113-3117)

Author Affiliations
From the Robert Wood Johnson Clinical Scholars Program (Dr Siscovick), the Departments of Medicine (Dr Inui), Epidemiology (Drs Weiss and Peterson), and Biostatistics (Dr Hallstrom), University of Washington, Seattle. Dr Siscovick is now with the University of North Carolina. Chapel Hill.

Footnotes
Reprint requests to Department of Medicine, Box 2, Wing C, 221H, University of North Carolina, Chapel Hill, NC 27514 (Dr Siscovick).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Morphology of Exertion-Triggered Plaque Rupture in Patients With Acute Coronary Syndrome: An Optical Coherence Tomography Study
Tanaka et al.
Circulation 2008;118:2368-2373.
ABSTRACT | FULL TEXT  

Genetic Determinants of Sudden Cardiac Death
Noseworthy and Newton-Cheh
Circulation 2008;118:1854-1863.
FULL TEXT  

Exercise capacity is a predictor of cardiovascular events in patients with type 2 diabetes mellitus
Seyoum et al.
Diabetes and Vascular Disease Research 2006;3:197-201.
ABSTRACT  

Reducing mortality from sudden cardiac death in the community: lessons from epidemiology and clinical applications research
Sotoodehnia et al.
Cardiovasc Res 2001;50:197-209.
ABSTRACT | FULL TEXT  

Leisure-Time Physical Activity and the Risk of Primary Cardiac Arrest
Lemaitre et al.
Arch Intern Med 1999;159:686-690.
ABSTRACT | FULL TEXT  

Plaque Rupture and Sudden Death Related to Exertion in Men With Coronary Artery Disease
Burke et al.
JAMA 1999;281:921-926.
ABSTRACT | FULL TEXT  

Mental Stress During Daily Life Triggers Myocardial Ischemia
Mittleman and Maclure
JAMA 1997;277:1558-1559.
ABSTRACT  

Self-reported Physical Activity Predicts Long-term Coronary Heart Disease and All-Cause Mortalities: Twenty-one-Year Follow-up of The Israeli Ischemic Heart Disease Study
Eaton et al.
Arch Fam Med 1995;4:323-329.
ABSTRACT  

Physical Activity Counseling for Healthy Adults as a Primary Preventive Intervention in the Clinical Setting: Report for the US Preventive Services Task Force
Harris et al.
JAMA 1989;261:3588-3598.
ABSTRACT  

A Natural History of Athleticism and Cardiovascular Health
Paffenbarger et al.
JAMA 1984;252:491-495.
ABSTRACT