High-dose intravenous immunoglobulin therapy in patients with immune thrombocytopenic purpura
R. R. Carroll, W. D. Noyes and C. S. Kitchens
Four patients with severe chronic immune thrombocytopenic purpura who were
refractory to all conventional therapy for that disorder were initially
seen with either refractory bleeding or the necessity for an operation. We
treated each of these patients with intravenous human serum immunoglobulin,
and three of the four patients had a rapid and substantial increase in
their platelet counts. This new method for ameliorating chronic immune
thrombocytopenic purpura deserves further study and consideration.
