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Endoscopic Retrograde CholangiopancreatographyDiagnosis of Cholelithiasis in Patients With Normal Gallbladder X-ray and Ultrasound Studies
Rama P. Venu, MD;
Joseph E. Geenen, MD;
James Toouli, MD;
Edward Stewart, MD;
Walter J. Hogan, MD
JAMA. 1983;249(6):758-761.
Abstract
The combination of a normal oral cholecystogram and ultrasound study of the gallbladder is considered adequate evidence to exclude cholelithiasis as a cause of biliarylike pain. We examined 206 patients with biliarylike pain and normal findings on cholecystogram and ultrasound study of the gallbladder by endoscopic retrograde cholangiopancreatography (ERCP). Of the 195 patients who had successful ERCP, 32 patients (group 1) had mild, transient abnormalities in liver function tests and 163 (group 2) had normal liver function test results. Small gallstones were demonstrated on ERCP examination in 25 of 32 group 1 patients and in four of 163 group 2 patients, all confirmed at surgery or endoscopic sphincterotomy. In conclusion, despite negative results on cholecystogram and ultrasound study of the gallbladder, patients with biliarylike pain and abnormal liver function test results should be evaluated further by diagnostic ERCP examination.
(JAMA 1983;249:758-761)
Author Affiliations
From the Departments of Medicine (Drs Venu, Geenen, Toouli, and Hogan) and Radiology (Dr Stewart), Medical College of Wisconsin, Milwaukee.
Footnotes
Presented at the Annual Meeting of the American Society for Gastrointestinal Endoscopy, New York, May 20, 1981.
Reprint requests to the Department of Medicine, Medical College of Wisconsin, 1333 College Ave, Racine, WI 53403 (Dr Geenen).
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