Middle ear disease and the practice of pediatrics. Burden during the first five years of life
D. W. Teele, J. O. Klein, B. Rosner, L. Bratton, G. R. Fisch, O. R. Mathieu, P. J. Porter, S. G. Starobin, L. D. Tarlin and R. P. Younes
To determine the burden on pediatricians imposed by disease of the middle
ear, we analyzed data from 2,570 children followed up prospectively since
birth. Disease of the middle ear accounted for a large proportion of all
visits made during the first five years of life, rising from 22.7% during
the first year to about 40% in years 4 and 5. About one visit in three made
for illness of any kind resulted in the diagnosis of disease of the middle
ear. Approximately three fourths of all visits to follow up any illness
were made to follow up disease of the middle ear. Disease of the middle ear
was diagnosed at between 5% and 10% of all well-baby visits. Children from
private practice averaged fewer visits for all reasons than did children
using a large neighborhood health center, but the proportions of visits
accounted for by disease of the middle ear were similar in both settings.
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Infect. Immun. 2007;75:4158-4172.
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Novel Sialic Acid Transporter of Haemophilus influenzae
Allen et al.
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Ultrasonic Detection of Middle Ear Effusion: A Preliminary Study
Discolo et al.
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Effect of Antibiotic Treatment Delay on Therapeutic Outcome of Experimental Acute Otitis Media Caused by Streptococcus pneumoniae Strains with Different Susceptibilities to Amoxicillin
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Host-derived sialic acid is incorporated into Haemophilus influenzae lipopolysaccharide and is a major virulence factor in experimental otitis media
Bouchet et al.
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Low Cord Blood Pneumococcal Antibody Concentrations Predict More Episodes of Otitis Media
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Safety and immunogenicity of a paediatric presentation of an influenza vaccine
Gonzalez et al.
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Human milk lactoferrin inactivates two putative colonization factors expressed by Haemophilus influenzae
Qiu et al.
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Parental Issues in Selection of Antimicrobial Agents for Infants and Children
Bauchner and Klein
CLIN PEDIATR 1997;36:201-205.
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Otitis Media in 2253 Pittsburgh-Area Infants: Prevalence and Risk Factors During the First Two Years of Life
Paradise et al.
Pediatrics 1997;99:318-333.
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An Association Between Recurrent Otitis Media in Infancy and Later Hyperactivity
Hagerman and Falkenstein
CLIN PEDIATR 1987;26:253-257.
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