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An Analysis of Its Potential Use in Medical Workers

John D. Hamilton, MD

JAMA. 1983;250(16):2145-2150.

Abstract
At the Duke University Medical Center, Durham, NC, there are approximately ten recognized hepatitis B virus (HBV) infections per year in employees. The hospital's hepatitis control program costs $91,995 per year, including costs for workman's compensation, hyperimmune globulin, laboratory tests, lost revenue, liability, personnel, and medical treatment. A program to immunize high-risk medical center personnel and to accommodate residual HBV problems in nonimmunized employees would cost $206,304 in the first year. By seven years the cumulative costs of an immunization program would equal those without a program and at ten years would be cost saving ($746,742 with program v $919,950 without a program). Given certain assumptions, HBV vaccine is a cost-beneficial alternative for a major employee health hazard.

(JAMA 1983;250:2145-2150)

Author Affiliations
From the Department of Medicine, Durham Veterans Administration Medical Center, and Duke University Medical Center, Durham, NC.

Footnotes
Reprint requests to Veterans Administration Medical Center, 508 Fulton St, Durham, NC 27705 (Dr Hamilton).

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