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Morris Traube, MD; Riyad Albibi, MD; Richard W. McCallum, MD

JAMA. 1983;250(19):2655-2659.

Abstract
Review of esophageal motility tracings performed during a three-year period yielded 112 patients who underwent the test because of chest pain of unclear etiology. Thirteen patients had high-amplitude peristaltic contractions. All 13 patients had pressurelike pain, ten had dysphagia, and six had symptoms of gastroesophageal reflux. The presence of an elevated lower esophageal sphincter pressure in five patients suggested a spectrum of hypertensive disorders of the esophagus variously affecting the body, the sphincter, or both. This latter subgroup responded to esophageal bougienage. Six patients had objective evidence for gastroesophageal reflux. These patients had at least partial relief from antireflux measures. High-amplitude peristaltic contractions should be considered in the differential diagnosis of noncardiac chest pain, since recognition of this entity can lead to appropriate management and symptom relief.

(JAMA 1983;250:2655-2659)

Author Affiliations
From the Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn.

Footnotes
Reprint requests to Yale University School of Medicine, Gastroenterology Section, 92 LMP, 333 Cedar St, PO Box 3333, New Haven, CT 06510 (Dr McCallum).

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