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David A. Katz, MD; Jonathan Ben-Ezra, MD; Stephen M. Factor, MD; Dikran S. Horoupian, MD; Sidney Goldfischer, MD

JAMA. 1983;250(19):2666-2669.

Abstract
A patient with an eight-year history of systemic lupus erythematosus (SLE) and recent onset of recurrent psychosis died after acute deterioration of cardiopulmonary status and level of consciousness. Autopsy disclosed massive pulmonary hemorrhage and unsuspected fat emboli in the lungs, kidney, and brain. This article discusses the significance of systemic fat embolism in SLE, with reference to corticosteroid therapy, fatal pulmonary hemorrhage, and lupus psychosis.

(JAMA 1983;250:2666-2669)

Author Affiliations
From the Departments of Neuropathology (Drs Katz and Horoupian) and Pathology (Drs Ben-Ezra, Factor, and Goldfischer), Albert Einstein College of Medicine and Bronx Municipal Hospital Center, Bronx, NY.

Footnotes
Reprint requests to Department of Neuropathology, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461 (Dr Horoupian).

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