This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (28)  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Stuart A. Chalew, MD; Judith V. McLaughlin, MD; James H. Mersey, MD; Anthony J. Adams, BSc; Marvin Cornblath, MD; A. Avinoam Kowarski, MD

JAMA. 1984;251(5):612-615.

Abstract
Patients with idiopathic postprandial syndrome (IPS) report recurrent postprandial episodes that resemble the clinical manifestations of hypoglycemia. In an effort to find objective criteria for diagnosis of IPS, we studied a group of patients with IPS and controls during an oral glucose tolerance test. Patients with IPS had a significantly lower mean glucose nadir and higher hypoglycemic index than controls. Although 74% of patients with IPS had glucose nadirs higher than 50 mg/dL, their responses of epinephrine, cortisol, growth hormone, glucagon, and norepinephrine were significantly higher than the respective changes in the controls. Of the five hormones, only the epinephrine response separated the patients from the controls without overlap. The epinephrine response may represent a valuable diagnostic criterion for this disorder.

(JAMA 1984;251:612-615)

Author Affiliations
From the Departments of Pediatric Endocrinology, University of Maryland School of Medicine, Baltimore (Drs Chalew, McLaughlin, Mersey, and Kowarski); The Johns Hopkins University School of Medicine, Baltimore (Dr Kowarski); and the National Institutes of Health, Bethesda, Md (Dr Cornblath and Mr Adams).

Footnotes
Reprint requests to University of Maryland School of Medicine, Howard Hall Tower 10-047, Baltimore, MD 21201 (Dr Kowarski).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Hypoglycemic Disorders
Service
NEJM 1995;332:1144-1152.
FULL TEXT  

Sugar and Children's Behavior
Schoenthaler et al.
NEJM 1994;330:1901-1904.
FULL TEXT  

Nutritional Biochemistry and Behavioral Disabilities
Fishbein and Meduski
J Learn Disabil 1987;20:505-512.
ABSTRACT  

Evaluation of Postprandial Symptoms
Service
JAMA 1984;252:1281-1281.
ABSTRACT