You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT JAMA
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 252 No. 14, October 12, 1984 TABLE OF CONTENTS
  JAMA
  •  Online Features
  ARTICLE
 This Article
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Contact me when this article is cited
 Related Content
 •Similar articles in JAMA

Death caused by recreational cocaine use. An update

R. E. Mittleman and C. V. Wetli

The epidemiologic, pathological, and toxicological findings of 60 cocaine-related overdose deaths from middle 1978 through 1982 were studied and compared with a previous publication by this office. In addition, 180 deaths where cocaine was an incidental toxicological finding are also discussed. Currently, the average street cocaine fatality victim is 29 years old, and 42% of the victims are female. Blacks comprise 39% of the cases. The blood cocaine concentration in "street cocaine" fatality victims averaged 6.2 mg/L with a wide range, necessitating careful interpretation of the toxicological results in conjunction with terminal events. Although autopsy findings were generally nonspecific, multiple needle-puncture marks with surrounding ecchymoses are typical of IV cocaine abuse. An increase in cocaine-related overdose deaths is anticipated because of its popularity, increasing availability, and, currently, the increased purity of street cocaine.

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Molecular Determinants of Cocaine Block of Human Ether-a-go-go-Related Gene Potassium Channels
Guo et al.
J. Pharmacol. Exp. Ther. 2006;317:865-874.
ABSTRACT | FULL TEXT  

Effects of Cocaine and Its Major Metabolites on the HERG-Encoded Potassium Channel
Ferreira et al.
J. Pharmacol. Exp. Ther. 2001;299:220-226.
ABSTRACT | FULL TEXT  

Cocaine Blocks HERG, but Not KvLQT1+minK, Potassium Channels
Zhang et al.
Mol. Pharmacol. 2001;59:1069-1076.
ABSTRACT | FULL TEXT  

Inhibition of Human Ether-A-Go-Go Potassium Channels by Cocaine
O'Leary
Mol. Pharmacol. 2001;59:269-277.
ABSTRACT | FULL TEXT  

Cocaine Increases the Endothelial Release of Immunoreactive Endothelin and Its Concentrations in Human Plasma and Urine : Reversal by Coincubation With {sigma}-Receptor Antagonists
Wilbert-Lampen et al.
Circulation 1998;98:385-390.
ABSTRACT | FULL TEXT  

Cocaine Blockade of the Acetylcholine-Activated Muscarinic K+ Channel in Ferret Cardiac Myocytes
Xiao and Morgan
J. Pharmacol. Exp. Ther. 1998;284:10-18.
ABSTRACT | FULL TEXT  

Adaptive Increase in D3 Dopamine Receptors in the Brain Reward Circuits of Human Cocaine Fatalities
Staley and Mash
J. Neurosci. 1996;16:6100-6106.
ABSTRACT | FULL TEXT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1984 American Medical Association. All Rights Reserved.