Vietnam veterans' risks for fathering babies with birth defects
J. D. Erickson, J. Mulinare, P. W. McClain, T. G. Fitch, L. M. James, A. B. McClearn and M. J. Adams Jr
Vietnam veterans' risks for fathering babies with major structural birth
defects were assessed using a case-control study. Information regarding
military service in Vietnam was obtained from interviews with mothers and
fathers of babies in case and control groups and from review of military
records. Vietnam veterans, in general, did not have an increased risk of
fathering babies with defects (all types combined; relative risk estimate,
0.97). Vietnam veterans who had greater estimated opportunities for Agent
Orange exposure did not seem to be at greater risk for fathering babies
with all types of defects combined. However, for a few specific types of
defects the estimated risks were higher for subgroups of Vietnam veterans
that may have had a greater likelihood of exposure to Agent Orange. These
seemingly higher risks could be chance events, the result of some
experience in the Vietnam service of the father, or the result of some
other unidentified risk factor.
Association between Agent Orange and birth defects: systematic review and meta-analysis
Ngo et al.
Int J Epidemiol 2006;35:1220-1230.
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Correa et al.
Pediatrics 2003;111:1146-1151.
ABSTRACT
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Oakes et al.
Toxicol Sci 2002;68:200-206.
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Botto et al.
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Honein et al.
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Regulations and Advisories
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Moore et al.
Pediatrics 1997;99:e11-e11.
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Finding the Causes of Birth Defects
Cordero
NEJM 1994;331:48-49.
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Skene et al.
Hum Exp Toxicol 1989;8:173-203.
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