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Stephen S. Feman, MD; Ron H. Tilford, MD

JAMA. 1985;253(17):2534-2537.

Abstract
Presumed ocular histoplasmosis syndrome is a multifocal choroiditis; it is not an uncommon cause of visual loss in patients who have positive cutaneous responses to histoplasmin tests. However, Histoplasma capsulatum infection is, most often, a pulmonary disease, or a systemically disseminated disorder, without visual symptoms. For this reason, a correspondence between the nonocular and ocular aspects of this disorder has been difficult to ascertain. In a series of eight patients with histoplasmosis, we found asymptomatic ocular lesions in six. We believe that the presence of asymptomatic lesions may have prevented earlier investigators from recognizing this correlation.

(JAMA 1985;253:2534-2537)

Author Affiliations
From the Department of Ophthalmology, Vanderbilt University, Nashville, Tenn.

Footnotes
Read in part before the Tennessee Medical Association, Knoxville, April 13, 1984.

Reprint requests to Department of Ophthalmology, Vanderbilt University, 21st and Garland, Nashville, TN 37232 (Dr Feman).

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