Serological response to syphilis treatment. A new analysis of old data
S. T. Brown, A. Zaidi, S. A. Larsen and G. H. Reynolds
One important aspect of the posttreatment evaluation of patients with early
syphilis is assessment of serological test results. Using information
previously collected from 818 patients in the Early Syphilis Study, we
evaluated the seroresponse of people treated for primary or secondary
syphilis. We generated curves describing the VDRL titer declines with time.
The VDRL titer declined approximately fourfold at three months and
eightfold at six months. These observations will allow clinicians to
identify treatment failures or reinfections at the earliest possible time
during their follow-up.
Reactivity in the Venereal Diseases Research Laboratory test and the Mercia(R) IgM enzyme immunoassay after treatment of early syphilis
McMillan and Young
Int J STD AIDS 2008;19:689-693.
ABSTRACT
| FULL TEXT
Primary syphilis
Eccleston et al.
Int J STD AIDS 2008;19:145-151.
ABSTRACT
| FULL TEXT
Syphilis
Lewis and Young
Sex. Transm. Infect. 2006;82:iv13-iv15.
FULL TEXT
Azithromycin versus Penicillin G Benzathine for Early Syphilis
Holmes
NEJM 2005;353:1291-1293.
FULL TEXT
A Decline in C6 Antibody Titer Occurs in Successfully Treated Patients with Culture-Confirmed Early Localized or Early Disseminated Lyme Borreliosis
Philipp et al.
CVI 2005;12:1069-1074.
ABSTRACT
| FULL TEXT
Syphilis: Review with Emphasis on Clinical, Epidemiologic, and Some Biologic Features
Singh and Romanowski
Clin. Microbiol. Rev. 1999;12:187-209.
ABSTRACT
| FULL TEXT
A Randomized Trial of Enhanced Therapy for Early Syphilis in Patients with and without Human Immunodeficiency Virus Infection
Rolfs et al.
NEJM 1997;337:307-314.
ABSTRACT
| FULL TEXT
The Response of Symptomatic Neurosyphilis to High-Dose Intravenous Penicillin G in Patients with Human Immunodeficiency Virus Infection
Gordon et al.
NEJM 1994;331:1469-1473.
ABSTRACT
| FULL TEXT
Sexually Transmitted Diseases
Albrecht and Wilkes
Journal of Pharmacy Practice 1991;4:237-246.
