This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (57)  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Karin B. Nelson, MD; Jonas H. Ellenberg, PhD

JAMA. 1985;254(11):1473-1479.

Abstract
In a large prospective study, we investigated predictors of moderately low (1,501 to 2,500 g) and very low (<1,501 g) birth weight. Maternal age, height, and socioeconomic status, related to moderately low birth weight on univariate analysis, were not on multivariate analysis significant predictors for either low-birth-weight outcome. The leading predictors of very low birth weight were low weight (<2,000 g) of last live birth, fetal malformation, nonwhite race, early vaginal bleeding, cigarette smoking, and chorionitis. Some of these were also predictors of moderately low birth weight. About 20% of births under 1,501 g could be attributed to chorionitis, a characteristic of less than 3% of the births. Of the major predictors of low birth weight, only prolonged rupture of membranes, chorionitis, and congenital malformations contributed to the risk of cerebral palsy beyond their contribution to the risk of low birth weight.

(JAMA 1985;254:1473-1479)

Author Affiliations
From the Developmental Neurology Branch and Biometry and Field Studies Branch, National Institute of Neurological and Communicative Disorders and Stroke, Bethesda, Md.

Footnotes
Reprint requests to Developmental Neurology Branch, National Institute of Neurological and Communicative Disorders and Stroke, 7550 Wisconsin Ave, Room 8C-04, Bethesda, MD 20205 (Dr Nelson).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Maternal Antenatal Complications and the Risk of Neonatal Cerebral White Matter Damage and Later Cerebral Palsy in Children Born at an Extremely Low Gestational Age
McElrath et al.
Am J Epidemiol 2009;170:819-828.
ABSTRACT | FULL TEXT  

Fetal Inflammatory Response and Brain Injury in the Preterm Newborn
Malaeb and Dammann
J Child Neurol 2009;24:1119-1126.
ABSTRACT  

Inhaled Nitric Oxide Therapy Decreases the Risk of Cerebral Palsy in Preterm Infants With Persistent Pulmonary Hypertension of the Newborn
Tanaka et al.
Pediatrics 2007;119:1159-1164.
ABSTRACT | FULL TEXT  

The Role of the Intrauterine and Perinatal Environment in Cerebral Palsy
Paneth et al.
NeoReviews 2005;6:e133-e140.
FULL TEXT  

Cerebral palsy and socioeconomic status: a retrospective cohort study
Sundrum et al.
Arch. Dis. Child. 2005;90:15-18.
ABSTRACT | FULL TEXT  

Intrauterine Exposure to Infection and Risk of Cerebral Palsy in Very Preterm Infants
Grether et al.
Arch Pediatr Adolesc Med 2003;157:26-32.
ABSTRACT | FULL TEXT  

Magnesium Sulfate and Prematurity
Kirschbaum
Reproductive Sciences 2002;9:58-59.
 

Parental Smoking Cessation Counseling: It's About Time
Christakis
Arch Pediatr Adolesc Med 2001;155:15-16.
FULL TEXT  

Chorioamnionitis as a Risk Factor for Cerebral Palsy: A Meta-analysis
Wu and Colford
JAMA 2000;284:1417-1424.
ABSTRACT | FULL TEXT  

Recent advances: Obstetrics
Roberts
BMJ 2000;321:33-35.
FULL TEXT  

Risk Factors for Cerebral Palsy in Very Low-Birthweight Infants in the 1980s and 1990s
Dunm-Wasowicz et al.
J Child Neurol 2000;15:417-420.
ABSTRACT  

Antenatal Glucocorticoid Treatment and Cystic Periventricular Leukomalacia in Very Premature Infants
Baud et al.
NEJM 1999;341:1190-1196.
ABSTRACT | FULL TEXT  

Perinatal Correlates of Cerebral Palsy and Other Neurologic Impairment Among Very Low Birth Weight Children
Wilson-Costello et al.
Pediatrics 1998;102:315-322.
ABSTRACT | FULL TEXT  

Maternal Infection and Cerebral Palsy in Infants of Normal Birth Weight
Grether and Nelson
JAMA 1997;278:207-211.
ABSTRACT  

Twinning and Neurologic Morbid035
Scheller and Nelson
Arch Pediatr Adolesc Med 1992;146:1110-1113.
ABSTRACT