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Susan E. Polchert, MD; Robert M. Morse, MD

JAMA. 1985;254(7):946-947.

Abstract
Addictive use of the stimulant drug pemoline caused a delusional disorder in a middle-aged man. Discontinuance of use of the drug promptly reversed the psychosis, which subsequently recurred when pemoline was again used. Pemoline seems to be an addictive drug and has an additional property that heretofore has been attributed mainly to amphetamines— precipitation of a paranoid psychosis.

(JAMA 1985;254:946-947)

Author Affiliations
From the Department of Psychiatry and Psychology, Mayo Clinic and Mayo Foundation, Rochester, Minn.

Footnotes
Reprint requests to Mayo Clinic, 200 First St SW, Rochester, MN 55905 (Dr Morse).

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