This Article  • References  • Full text PDF  • Correction  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Culture vs Antibody Methods

James A. Kellogg, PhD; John P. Manzella, MD

JAMA. 1986;255(19):2638-2642.

Abstract
Much controversy has existed concerning the clinical significance of small numbers of group A streptococci (eg, one to ten or even 50 colonies) recovered in culture. The relative quantity of streptococci recovered is, in part, technique dependent. This review documents the need for sensitive throat culture technology, addresses technical problems associated with the culture procedure, and, in light of these problems, explores the need for very carefully performed studies on streptococcal antigen detection kits before their implementation as a routine test either in physicians' offices or in microbiology laboratories.

(JAMA 1986;255:2638-2642)

Author Affiliations
From the Clinical Microbiology Laboratory (Dr Kellogg) and the Division of Infectious Diseases, Department of Internal Medicine (Dr Manzella), York (Pa) Hospital.

Footnotes
Reprint requests to Clinical Microbiology Laboratory, York Hospital, 1001 S George St, York, PA 17405 (Dr Kellogg).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Recovering Streptococci from the Throat, a Practical Alternative to Direct Plating in Remote Tropical Communities
McDonald et al.
J. Clin. Microbiol. 2006;44:547-552.
ABSTRACT | FULL TEXT  

Diagnosis and Management of Adults with Pharyngitis: A Cost-Effectiveness Analysis
Neuner et al.
ANN INTERN MED 2003;139:113-122.
ABSTRACT | FULL TEXT  

Principles of Appropriate Antibiotic Use for Acute Pharyngitis in Adults: Background
Cooper et al.
ANN INTERN MED 2001;134:509-517.
ABSTRACT | FULL TEXT  

Pediatricians' Diagnostic Approach to Pharyngitis and Impact of CLIA 1988 on Office Diagnostic Tests
Schwartz et al.
JAMA 1994;271:234-238.
ABSTRACT  

Estimating the Predictive Value Of a Diagnostic Test: How To Prevent Misleading or Confusing Results
O'Marcaigh and Jacobson
CLIN PEDIATR 1993;32:485-491.
ABSTRACT  

Comparison of an Immunochromatographic Method for Rapid Identification of Group A Streptococcal Antigen With Culture Method
Ehrlich et al.
Arch Fam Med 1993;2:866-869.
ABSTRACT  

The Impact of a Rapid Screen for Streptococcal Pharyngitis on Clinical Decision Making in the Emergency Department
Hedges et al.
Med Decis Making 1991;11:119-124.
ABSTRACT  

Streptococcal Pharyngitis: Comparison of Latex Agglutination and Throat Culture
White et al.
CLIN PEDIATR 1988;27:431-434.
ABSTRACT  

Evaluating Rapid Tests for Streptococcal Pharyngitis: The Apparent Accuracy of a Diagnostic Test When There Are Errors in the Standard of Comparison
Deneef
Med Decis Making 1987;7:92-96.
ABSTRACT  

The Management of Sore Throat: Adjusting to Success
Dans
JAMA 1986;256:3392-3393.
ABSTRACT  

Testing for Streptococcal Pharyngitis
Odio
JAMA 1986;256:2516-2516.
ABSTRACT