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Sara Leiba, MD; Bella Schindel, MD; Ruth Weinstein, MD; laron Lidor, MD; Shmuel Friedman, MD; Shoshana Matz, MD

JAMA. 1986;255(2):230-232.

Abstract
A 37-year-old woman undergoing endocrine evaluation during her seventh pregnancy because of headaches, weakness, and hyponatremia was found to have central hypoadrenalism and hypothyroidism. Computed tomography showed a pituitary mass with suprasellar extension but her visual fields were intact. She was treated conservatively with hydrocortisone acetate and levothyroxine sodium until 38 weeks of gestation, when healthy twins were delivered by cesarean section. A few months later, her pituitary function improved, with a significant increase in the adrenocorticotropic hormone level, normal values of basal thyroid-stimulating hormone, growth hormone, and gonadotropins and of their functional reserves, and only a slight elevation in the prolactin level. A repeated computed tomographic scan showed disappearance of the pituitary mass.

(JAMA 1986;255:230-232)

Author Affiliations
From the Departments of Endocrinology (Drs Leiba, Schindel, and Weinstein) and Gynecology and Obstetrics (Drs Lidor and Friedman) and the Unit of Computerized Tomography Scan (Dr Matz), Beilinson Medical Center and the Sackler School of Medicine, Tel Aviv University, Petah Tiqva, Israel.

Footnotes
Reprints not available.

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