2,3,7,8-Tetrachlorodibenzo-p-dioxin levels in adipose tissue of exposed and control persons in Missouri. An interim report
D. G. Patterson Jr, R. E. Hoffman, L. L. Needham, D. W. Roberts, J. R. Bagby, J. L. Pirkle, H. Falk, E. J. Sampson and V. N. Houk
The compound 2,3,7,8-tetrachlorodibenzo-p-dioxin, commonly known as dioxin,
was measured in the adipose tissue of 39 persons with a history of
residential, recreational, or occupational exposure in Missouri and in 57
persons in a control group. All participants had detectable levels of
2,3,7,8-tetrachlorodibenzo-p-dioxin in their adipose tissue, but the
exposed group had significantly higher levels. Levels of six of the exposed
persons were more than five times greater than the level of the highest
control. Measuring 2,3,7,8-tetrachlorodibenzo-p-dioxin in adipose tissue
provides a much improved index of exposure, an important advance for
research studies evaluating the possible health effects of this compound.
