This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

A Report of Two Cases

Jack G. Copeland, MD; Mark M. Levinson, MD; Richard Smith, MSEE, CEE; Timothy B. Icenogle, MD; Cecil Vaughn, MD; Kevin Cheng, DDS; Richard Ott, MD; Robert W. Emery, MD

JAMA. 1986;256(21):2991-2995.

Abstract
In 1985, at the University of Arizona, Tucson, two attempts were made to "bridge" patients from impending death to heart transplantation, using orthotopically positioned total artificial hearts. The first attempt, using an unapproved device on an emergency basis, failed after transplantation because of severe pulmonary edema and Pseudomonas pneumonia and the apparent transmission of a Pseudomonas infection from donor to recipient. The second experience, using a Jarvik-7 device, led to stable support for nine days with one major complication, a reversible neurologic deficit with no associated computed tomographic scan abnormality. This patient survived cardiac transplantation and, after being successfully treated for complications, has made a full recovery and returned to full-time work.

(JAMA 1986;256:2991-2995)

Author Affiliations
From the Section of Cardiovascular and Thoracic Surgery, Department of Surgery, Arizona Health Sciences Center (Drs Copeland, Levinson, cenogle, Ott, and Emery), and the Artificial Heart Program, University Medical Center (Mr Smith), Tucson; and the St Luke's Heart and Lung Center, Phoenix (Dr Vaughn). Dr Cheng is in private practice in Tempe, Ariz.

Footnotes
Reprint requests to Section of Cardiovascular and Thoracic Surgery, Department of Surgery, 1501 N Campbell, Arizona Health Sciences Center, Tucson, AZ 85724 (Dr Copeland).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

CardioWest (Jarvik) Total Artificial Heart: A Single-Center Experience With 42 Patients
Roussel et al.
Ann. Thorac. Surg. 2009;87:124-130.
ABSTRACT | FULL TEXT  

Arizona experience with CardioWest total artificial heart bridge to transplantation
Copeland et al.
Ann. Thorac. Surg. 1999;68:756-760.
ABSTRACT | FULL TEXT  

Implantable Left Ventricular Assist Devices
Goldstein et al.
NEJM 1998;339:1522-1533.
FULL TEXT  

The CardioWest total artificial heart bridge to transplantation: 1993 to 1996 National Trial
Copeland et al.
Ann. Thorac. Surg. 1998;66:1662-1669.
ABSTRACT | FULL TEXT  

International experience with the CardioWest total artificial heart as a bridge to heart transplantation
Arabia et al.
Eur. J. Cardiothorac. Surg. 1997;11:S5-S10.
ABSTRACT  

Mechanical circulatory support: lessons from a single centre
El-Banayosy et al.
Perfusion 1996;11:93-102.
ABSTRACT  

Eight years' experience with bridging to cardiac transplantation
Pennington et al.
J. Thorac. Cardiovasc. Surg. 1994;107:472-481.
ABSTRACT | FULL TEXT